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Weight loss reduces the risk of colorectal cancer, according to a study
27 Jan' 21

Weight loss reduces the risk of colorectal cancer, according to a study

 

Weight loss reduces the risk of colorectal cancer, according to a study.  

The results of a recent study offer some light on whether decreasing weight lowers cancer risk. Obese and overweight people who lose weight may have a lower risk of developing colorectal adenoma, a benign growth or polyp in the colon or rectum that can lead to colorectal cancer, according to a study published in 'JNCI Cancer Spectrum' by Oxford University Press.  

Colorectal cancer is the third most common cancer in men and women in the United States and the third leading cause of cancer death. 

 

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Obesity has long been known to increase the risk of colorectal cancer and adenoma.  

Doctors routinely urge overweight and obese patients to lose weight. Although weight loss has been shown to have some health advantages, it is unknown whether it can reduce the incidence of colorectal adenoma. The majority of studies have only looked at colorectal adenoma risk in connection to obesity or BMI measured at a single moment in time, with fewer studies looking at the influence of weight change. 

The Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial used self-reported weight data to investigate weight change (including both weight gain and weight loss) during three periods of adulthood in association with colorectal adenoma.  

From 1993 to 2001, the experiment enrolled 154,942 men and women in the United States, ranging in age from 55 to 74, to assess the efficacy of various screening procedures in reducing death from various malignancies. Participants in the screening arm of the trial, who got a colorectal cancer screening test at baseline and again 3 or 5 years later, were used in this analysis. 

 

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Weight gain in adulthood was also connected to an increased risk of adenoma, especially if the gain was greater than 6.6 pounds in 5 years, according to the researchers.  

Males appeared to lose more weight and gain more weight than females, according to the data. According to the researchers, the data show how important it is to maintain a healthy weight throughout life in order to avoid colorectal adenoma. Adults who are overweight or obese may be able to reduce their heart disease risk as well.  

"Our findings suggest that preventing weight increase in adulthood may lower the risk of developing a precancerous growth known as a colon adenoma, which may lower the risk of colorectal cancer," said Kathryn Hughes Barry, the study's senior author. "We would not promote weight loss for all adults based on our findings." However, the findings show that individuals who are overweight or obese may benefit from weight loss." 

 

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